Avid Reader asked below in the comments what the difference was. IMO - here are the basics.
1 - Purpose
The ARC's purpose is to be read by a reviewer or bookseller to create buzz about an upcoming release.
The second hand book is being sold after (often well after) the release date by a reader who has already paid full price for it.
2 - Money
If an ARC is sold - neither the author or publisher get any money from the sale.
If a second hand book is sold, the author and publisher have already made the money on it from the first sale.
3 - Implied Trust
An ARC is given to a reviewer in exchange for a review. If this abuse keeps happening, the publishers will stop sending ARCs and then all of us decent reviewers will miss out.
A second hand book belongs to the reader that bought it - they can then do whatever they want with it. The author hasn't trusted them to do anything but buy it. They don't even have to read it.
In a perfect world for authors - there would be no second hand books either, but ultimately they realise that the word of mouth from buying a book second hand can work and grow them new fans.
...and no - the NOT FOR SALE isn't on there because it's uncorrected. It's on there for the reasons stated above, because it is NOT a book - it's a printed out manuscript, a sneak peak for certain priviledged people before it goes on sale.
make sense?
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In contrast to most antidepressant medications, which can take several weeks to reduce depressive symptoms, ketamine — a commonly used veterinary anesthetic — can lift a person out of deep depression within minutes of its administration, and its effects can last several weeks. Researchers have long-wondered how ketamine can both act quickly and be so long-lasting.
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Now, researchers led by Mark Rasenick, distinguished professor of physiology and psychiatry at the University of Illinois at Chicago College of Medicine, describe the molecular mechanisms behind ketamine’s ability to squash depression and keep it at bay. They report their findings in the journal Molecular Psychiatry.
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Two-thirds of participants in clinical studies who did not respond to traditional antidepressants experienced fast and lasting resolution of their depressive symptoms after being given ketamine intravenously, Rasenick explained. The effects of ketamine typically lasted about a week — much longer than would be expected with ketamine’s six-hour half-life in the body.
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In the earlier research, when Rasenick exposed rat brain cells to SSRIs, the drug accumulated in the lipid rafts, and G proteins moved out of the rafts. The movement was gradual, over the span of several days, which Rasenick thinks is the reason why SSRIs and most other antidepressants can take a long time to begin working. Buy Ketamine crystals Online, | buy crystal ketamine Europe
In his current research, Rasenick and his colleagues performed a similar experiment with ketamine and noticed that the G proteins left the rafts much faster. G proteins began migrating out of the lipid rafts within 15 minutes. And the long-lasting effects of ketamine may be due to the fact that the G proteins were very slow to move back into the lipid rafts, Rasenick explained. Buy ketamine rotexmedica in Europe, buy rotexmedica ketamine Online, | buy rotexmedica ketamine Netherland